Mediators of inflammation involved in UVB erythema

T Terui; H Tagami

doi:10.1016/s0923-1811(99)00070-5

Mediators of inflammation involved in UVB erythema

J Dermatol Sci. 2000 Mar:23 Suppl 1:S1-5. doi: 10.1016/s0923-1811(99)00070-5.

Authors

T Terui¹, H Tagami

Affiliation

¹ Department of Dermatology, Tohoku University School of Medicine, Seiryo-machi 1-1, Aoba-ku, Sendai, Japan. terui@mail.cc.tohoku.ac.jp

PMID: 10764982
DOI: 10.1016/s0923-1811(99)00070-5

Abstract

In this review, we discuss the mediators and inflammatory cells involved in UVB-induced inflammatory changes phase by phase. We especially stress the importance of IFNgamma secreted by activated CD4(+) T cells in the development of UVB erythema. We also speculate on the mechanism underlying regression of UVB erythema.

Publication types

Research Support, Non-U.S. Gov't
Review

MeSH terms

Animals
CD4-Positive T-Lymphocytes / immunology
Complement Activation
Cytokines / biosynthesis
Erythema / etiology*
Erythema / immunology
Humans
Inflammation Mediators / physiology*
Interferon-gamma / biosynthesis
Neutrophils / immunology
Tumor Necrosis Factor-alpha / biosynthesis
Ultraviolet Rays / adverse effects*

Substances

Cytokines
Inflammation Mediators
Tumor Necrosis Factor-alpha
Interferon-gamma