Status-like recurrent pilomotor seizures: case report and review of the literature

J Neurol Neurosurg Psychiatry. 2000 May;68(5):647-9. doi: 10.1136/jnnp.68.5.647.


A diabetic 66 year old man who presented with pilomotor seizures in his right hemibody is described. The seizures recurred with an increasing frequency, leading to a status-like condition associated with Korsakoff's syndrome. An EEG was performed and several electroclinical seizures were recorded. Brain MRI was negative. The patient, who was treated with carbamazepine, became seizure free after 1 week. Memory and behaviour gradually returned to normal within 3 weeks. There was no further neurological episode during an 8 year follow up. Hyperosmolar, non-ketotic hyperglycaemia was considered to be the cause of the seizures. The pathophysiology of pilomotor seizures is discussed and the literature on the subject reviewed.

Publication types

  • Case Reports
  • Review

MeSH terms

  • Aged
  • Anticonvulsants / therapeutic use
  • Carbamazepine / therapeutic use
  • Diabetes Complications
  • Electroencephalography
  • Humans
  • Hyperglycemia / complications
  • Korsakoff Syndrome / etiology*
  • Male
  • Seizures / drug therapy
  • Seizures / etiology
  • Seizures / physiopathology*
  • Status Epilepticus / drug therapy
  • Status Epilepticus / etiology
  • Status Epilepticus / physiopathology*
  • Treatment Outcome


  • Anticonvulsants
  • Carbamazepine