Abstract
We report the case of a 62-year-old man with nephrotic syndrome associated with stage B chronic lymphocytic leukemia (CLL). Kappa Bence Jones proteinuria and the glomerular deposition of kappa-light chain were observed. Although treatment with cyclophosphamide and prednisolone tended to reduce the level of proteinuria, the administration of angiotensin-converting enzyme inhibitor, enalapril, resulted in complete remission of nephrotic syndrome.
MeSH terms
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Angiotensin-Converting Enzyme Inhibitors / therapeutic use*
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Biopsy
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Cyclophosphamide / therapeutic use
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Drug Therapy, Combination
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Enalapril / therapeutic use
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Humans
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Immunosuppressive Agents / therapeutic use*
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Leukemia, Lymphocytic, Chronic, B-Cell / complications*
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Leukemia, Lymphocytic, Chronic, B-Cell / drug therapy
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Leukemia, Lymphocytic, Chronic, B-Cell / pathology
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Male
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Middle Aged
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Nephrotic Syndrome / drug therapy*
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Nephrotic Syndrome / etiology
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Nephrotic Syndrome / pathology
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Prednisolone / therapeutic use
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Remission Induction
Substances
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Angiotensin-Converting Enzyme Inhibitors
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Immunosuppressive Agents
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Enalapril
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Cyclophosphamide
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Prednisolone