Patient with insufficient glandular tissue experiences milk supply increase attributed to progesterone treatment for luteal phase defect

J Hum Lact. 1999 Dec;15(4):339-43. doi: 10.1177/089033449901500415.


A case report is presented on the experience of a mother diagnosed with insufficient glandular tissue at 3 months postpartum with her first child who then went on to breastfeed her second child (fifth pregnancy) without supplementation of any kind. The mother had difficulty becoming pregnant and maintaining a pregnancy. She was diagnosed with a luteal phase defect and was thus treated with natural progesterone during her fifth pregnancy. The authors speculate that this treatment may have stimulated the development of her mammary alveolar cells, allowing lactation to progress normally.

Publication types

  • Case Reports

MeSH terms

  • Adult
  • Bottle Feeding
  • Breast / abnormalities*
  • Breast / drug effects*
  • Decision Trees
  • Failure to Thrive / diagnosis
  • Failure to Thrive / etiology
  • Female
  • Humans
  • Infant Food
  • Infertility, Female / complications
  • Infertility, Female / drug therapy*
  • Lactation Disorders / etiology*
  • Luteal Phase / drug effects*
  • Pregnancy
  • Progesterone / therapeutic use*


  • Progesterone