Postoperative lavage and on demand surgical intervention in the treatment of acute necrotizing pancreatitis

Acta Chir Belg. 2000 Feb;100(1):16-20.

Abstract

Objective: To analyse our experience with a combined approach of postoperative local lavage and on demand surgical intervention in the treatment of acute necrotizing pancreatitis.

Patients and methods: All patients operated on for acute pancreatitis in a tertiary hospital between June 1993 and July 1997 were studied retrospectively. Demographic data, Ranson score, APACHE II score at admission were recorded. Hospital charts and clinical courses were reviewed.

Results: Seventeen patients were treated surgically because of end stage multiple organ failure (MOF) (n = 13) or infected necrosis (n = 4). APACHE II and Ranson scores were 26.2 +/- 9.25 and 7.33 +/- 1.35 respectively. All patients had protracted clinical courses, and required aggressive intensive care therapy. Forty-eight surgical interventions were performed in 17 patients. Early mortality was 36 percent. Complications were numerous, and mostly consisted of intra-abdominal abscesses. Young age (under 55) was associated with significantly better outcome (22% vs. 87% mortality, p = 0.015).

Conclusion: Continuous local lavage after surgical debridement, with on demand re-laparotomy, proves to be a valuable approach in patients with necrotizing pancreatitis with acceptable morbidity and mortality rates. It appears however, that the role of surgery for acute pancreatitis is limited to patients with infected necrosis or end stage MOF.

Publication types

  • Comparative Study

MeSH terms

  • Adult
  • Aged
  • Combined Modality Therapy
  • Debridement / methods*
  • Debridement / mortality
  • Female
  • Humans
  • Male
  • Middle Aged
  • Pancreatitis, Acute Necrotizing / diagnosis
  • Pancreatitis, Acute Necrotizing / mortality
  • Pancreatitis, Acute Necrotizing / surgery*
  • Peritoneal Lavage / methods*
  • Postoperative Care
  • Postoperative Complications
  • Probability
  • Prognosis
  • Retrospective Studies
  • Statistics, Nonparametric
  • Survival Rate
  • Tomography, X-Ray Computed
  • Treatment Outcome