Raloxifene: a new choice for treating and preventing osteoporosis

Cleve Clin J Med. 2000 Apr;67(4):273-80. doi: 10.3949/ccjm.67.4.273.

Abstract

Selective estrogen receptor modulators (SERMs) are a new class of drugs that provide a new option for addressing the health challenges of postmenopausal women. This review discusses the proposed mechanism of action of SERMs and describes clinical findings on raloxifene, a SERM now available for treating and preventing osteoporosis.

Publication types

  • Research Support, Non-U.S. Gov't
  • Review

MeSH terms

  • Aged
  • Calcitonin / therapeutic use
  • Diphosphonates / therapeutic use
  • Estrogen Replacement Therapy
  • Female
  • Humans
  • Middle Aged
  • Osteoporosis / drug therapy*
  • Osteoporosis / prevention & control*
  • Postmenopause
  • Raloxifene Hydrochloride / adverse effects
  • Raloxifene Hydrochloride / therapeutic use*
  • Risk Factors
  • Selective Estrogen Receptor Modulators / adverse effects
  • Selective Estrogen Receptor Modulators / therapeutic use*

Substances

  • Diphosphonates
  • Selective Estrogen Receptor Modulators
  • Raloxifene Hydrochloride
  • Calcitonin