Correlates and impact on outcomes of worsening renal function in patients > or =65 years of age with heart failure

Am J Cardiol. 2000 May 1;85(9):1110-3. doi: 10.1016/s0002-9149(00)00705-0.


1.5 mg/dl. Based on the number of these factors, a patient's risk for developing worsening renal function ranged between 16% (< or =1 factor) and 53% (> or =5 factors). After adjusting for confounding effects, worsening renal function was associated with a significantly longer length of stay by 2.3 days, higher in-hospital cost by $1,758, and an increased risk of in-hospital mortality (odds ratio 2.72; 95% confidence interval 1.62 to 4.58). In conclusion, worsening renal function, an event that frequently occurs in elderly patients hospitalized with heart failure, confers a substantial burden to patients and the healthcare system and can be predicted by 6 admission characteristics.

Publication types

  • Research Support, U.S. Gov't, Non-P.H.S.

MeSH terms

  • Aged
  • Aged, 80 and over
  • Creatinine / blood
  • Female
  • Heart Failure / physiopathology*
  • Humans
  • Kidney / physiology*
  • Logistic Models
  • Male
  • Middle Aged


  • Creatinine