Sox Neuro, a New Drosophila Sox Gene Expressed in the Developing Central Nervous System

Mech Dev. 2000 May;93(1-2):215-9. doi: 10.1016/s0925-4773(00)00268-9.

Abstract

We describe the identification and detailed expression pattern of a second Drosophila Sox gene, SoxNeuro (SoxN), highly related to mammalian group B Sox1, 2, 3 genes. SoxN is expressed in a highly dynamic pattern during embyogenesis, being associated with the development of the central nervous system (CNS), from the early steps onwards. We present strong evidence that the early SoxN neuroectoderm expression is controlled by the zygotic dorso-ventral patterning genes (dpp, sog, brk, twi).

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Amino Acid Sequence
  • Animals
  • Base Sequence
  • Cloning, Molecular
  • DNA, Complementary
  • Drosophila / embryology*
  • Drosophila / genetics
  • Drosophila Proteins*
  • Gene Expression
  • High Mobility Group Proteins / genetics*
  • Humans
  • Insect Proteins / genetics*
  • Molecular Sequence Data
  • SOX Transcription Factors
  • Transcription Factors / genetics*

Substances

  • DNA, Complementary
  • Drosophila Proteins
  • High Mobility Group Proteins
  • Insect Proteins
  • SOX Transcription Factors
  • SoxN protein, Drosophila
  • Transcription Factors

Associated data

  • GENBANK/AJ252124