Malignant melanoma arising in a choroidal magnacellular nevus (melanocytoma)

Can J Ophthalmol. 1976 Apr;11(2):140-6.


A case is presented of a 55-year-old Caucasian male whose right eye was enucleated for a mixed spindle-A and spindle-B malignant melanoma in 1967. The ophthalmoscopic picture, fluorescein angiography, and overlying peculiar orange pigmentation were suggestive of a malignant lesion. Study of serial sections of the entire lesion made possible the histologic reconstruction of the lesion, clinicopathologic correlation of the yellow-orange pigment, and the location of the nevus and mixed spindle-cell melanoma components.

Publication types

  • Case Reports

MeSH terms

  • Cell Transformation, Neoplastic / pathology
  • Choroid Neoplasms / pathology*
  • Humans
  • Male
  • Melanoma / pathology*
  • Middle Aged
  • Nevus, Pigmented / pathology*