Alpha-1-antitrypsin deficiency, emphysema, cirrhosis, and intestinal mucosal atrophy

JAMA. 1975 Jan 20;231(3):273-6.

Abstract

An elderly man with long-standing pulmonary emphysema was seen with recent onset of steatorrhea and ascites. He had very low levels of serum alpha1-antitrypsin, hepatic cirrhosis, and intestinal mucosal atrophy. We believe this this combination of findings did not occur by chance.

MeSH terms

  • Atrophy / pathology
  • Autopsy
  • Biopsy
  • Celiac Disease / complications
  • Celiac Disease / etiology*
  • Humans
  • Intestinal Mucosa / pathology*
  • Intestine, Small
  • Liver / pathology
  • Liver Cirrhosis / complications
  • Liver Cirrhosis / etiology*
  • Liver Cirrhosis / pathology
  • Male
  • Microscopy, Electron
  • Middle Aged
  • Pulmonary Emphysema / complications
  • Pulmonary Emphysema / etiology*
  • alpha 1-Antitrypsin

Substances

  • alpha 1-Antitrypsin