Effect of ivermectin on the brown dog tick, Rhipicephalus sanguineus

J Egypt Soc Parasitol. 2000 Apr;30(1):117-24.

Abstract

Ivermectin (Ivomec) proved to be effective in controlling R. sanguineus. All brown dog ticks infesting the treated dogs (subcutaneous injections) with 1.5 ml or 2 ml/50 kg dropped off within 4 or 3 days respectively. The dropped off ticks were completely inactive and died within one day or two. Ticks exposed to filter papers impregnated with 100 micrograms/ml (66.67%) died within four days. A dose of 1.5-2 microliters/50 kg eradicated Toxocara canis infection in four dogs, and caused shrinkage of Dipylidium caninum gravid segments in three. A general discussion was given with special reference to the contraindications and side effects of ivermectin particularly for human usage.

MeSH terms

  • Animals
  • Dogs
  • Female
  • Insecticides / pharmacology*
  • Ivermectin / pharmacology*
  • Male
  • Ticks / drug effects*

Substances

  • Insecticides
  • Ivermectin