N-3 fatty acids from fish and coronary artery disease: implications for public health

Public Health Nutr. 2000 Mar;3(1):91-8. doi: 10.1017/s1368980000000112.


Objective: To review and discuss the effect of n-3 polyunsaturated fatty acids (PUFA) from fish in the prevention and, primarily, in the treatment of coronary artery disease (CAD).

Design: Overview of the literature.

Setting: Denmark.

Results: There is good evidence that fish consumption may reduce the risk of CAD.

Conclusions: Fish can be recommended to reduce the risk of CAD both in healthy subjects and in patients with a high risk of CAD or with documented CAD. The use of fish oil concentrates can not be recommended in general, but may be considered in patients after a myocardial infarction or in patients with hypertriglyceridaemia. An increased intake of n-3 polyunsaturated fatty acids from fish may have substantial implications for public health and health economy by decreasing the risk of coronary events and sudden cardiac death.

Publication types

  • Research Support, Non-U.S. Gov't
  • Review

MeSH terms

  • Coronary Disease / diet therapy*
  • Coronary Disease / epidemiology
  • Coronary Disease / prevention & control*
  • Death, Sudden, Cardiac / prevention & control
  • Denmark / epidemiology
  • Dietary Fats / administration & dosage*
  • Fatty Acids, Omega-3 / administration & dosage*
  • Fish Oils / administration & dosage
  • Humans
  • Public Health*
  • Risk Factors


  • Dietary Fats
  • Fatty Acids, Omega-3
  • Fish Oils