High-resolution segmented EPI in a motor task fMRI study

Magn Reson Imaging. 2000 May;18(4):405-9. doi: 10.1016/s0730-725x(00)00127-2.


A high-resolution gradient echo, multi-slice segmented echo planar imaging method was used for functional MRI (fMRI) using a motor task at 1.5 Tesla. Functional images with an in-plane resolution of 1 mm and slice thickness of 4 mm were obtained with good white-gray matter contrast. The multi-shot approach, combined with a short total readout period of 82 ms, limits blurring effects for short T(2)(*) tissues (such as gray matter), assuring truly high-resolution images. In all subjects, motor functions were clearly depicted in the contralateral central sulcus over several slices and sometimes activation was detected in the supplementary motor area and/or ipsilateral central sulcus. The average signal change of 11+/-3% was much higher than in standard low-resolution fMRI EPI experiments, as a result of larger relative blood fractions.

MeSH terms

  • Adult
  • Brain / physiology*
  • Brain Mapping
  • Echo-Planar Imaging*
  • Humans
  • Magnetic Resonance Imaging*
  • Movement / physiology*
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