Role of tumour markers in monitoring epithelial ovarian cancer

Br J Cancer. 2000 May;82(9):1535-8. doi: 10.1054/bjoc.2000.1174.


Currently the only tumour marker to have a well-defined and validated role in the management of ovarian cancer is CA125. Changes in the level of CA125 can be used as a reliable indication of response or progression according to various criteria, but it does not yet have a clear place in diagnosis or prognosis. Its value as part of a screening tool and during routine follow-up remain the subject of ongoing trials. Other markers remain experimental and do not have a well-defined contribution to make at present.

Publication types

  • Review

MeSH terms

  • Biomarkers, Tumor / analysis*
  • CA-125 Antigen / blood*
  • Female
  • Humans
  • Monitoring, Physiologic
  • Ovarian Neoplasms / blood
  • Ovarian Neoplasms / diagnosis
  • Ovarian Neoplasms / pathology*
  • Recurrence


  • Biomarkers, Tumor
  • CA-125 Antigen