Transpupillary thermotherapy

Semin Ophthalmol. 1999 Mar;14(1):11-8. doi: 10.3109/08820539909056058.


Hyperthermia has long been recognized as potentially useful in the treatment of human neoplasms. Only recently has technology allowed hyperthermic treatment to be delivered to ocular structures in the form of ultrasound, microwave, or ferromagnetic energy. A novel technique, transpupillary thermotherapy, allows the direct application of hyperthermic energy to posterior segment ocular structures. The treatment of two posterior segment diseases, choroidal melanoma and choroidal neovascularization attributable to age related macular degeneration, are reviewed in this article.

Publication types

  • Review

MeSH terms

  • Choroid Neoplasms / pathology
  • Choroid Neoplasms / therapy*
  • Choroidal Neovascularization / etiology
  • Choroidal Neovascularization / pathology
  • Choroidal Neovascularization / therapy*
  • Fluorescein Angiography
  • Humans
  • Hyperthermia, Induced / methods*
  • Macular Degeneration / complications
  • Macular Degeneration / pathology
  • Melanoma / pathology
  • Melanoma / therapy*
  • Pupil