Neonatal Haemophilus influenzae infection. Report of eight cases and review of the literature

Am J Dis Child. 1975 Jan;129(1):57-62. doi: 10.1001/archpedi.1975.02120380037009.

Abstract

Eight cases of neonatal Haemophilus influenzae infection occurred at Colorado General Hospital during a 3 1/2-year period. Four of the cases were due to nontypable organisms and four to type b organisms. Four were bacteremic, only two of which were type b. None of the patients had meningitis. In all instances, maternal genital tract cultures yielded H infleuzae that, when tested, was of the same serotype as the infant isolate. A survey of cervical cultures among normal and pregnant women yielded H influenzae in less than 1%. There are several possible reasons for the disparity between the apparent high incidence of neonatal infection and low prevalence of maternal carriage.

Publication types

  • Research Support, U.S. Gov't, P.H.S.

MeSH terms

  • Adolescent
  • Adult
  • Ampicillin / therapeutic use
  • Antibodies, Bacterial / analysis
  • Antigens, Bacterial / analysis
  • Cervix Uteri / microbiology
  • Female
  • Genitalia, Female / microbiology
  • Haemophilus Infections / congenital*
  • Haemophilus Infections / drug therapy
  • Haemophilus influenzae / isolation & purification
  • Humans
  • Infant, Newborn
  • Infant, Newborn, Diseases* / drug therapy
  • Infant, Newborn, Diseases* / etiology
  • Infant, Newborn, Diseases* / microbiology
  • Male
  • Pregnancy
  • Pregnancy Complications, Infectious / drug therapy

Substances

  • Antibodies, Bacterial
  • Antigens, Bacterial
  • Ampicillin