Manipulating immune responses with immunosuppressive agents that target NFAT

Immunity. 2000 Apr;12(4):359-72. doi: 10.1016/s1074-7613(00)80188-0.
No abstract available

Publication types

  • Comparative Study
  • Research Support, Non-U.S. Gov't
  • Research Support, U.S. Gov't, P.H.S.
  • Review

MeSH terms

  • Animals
  • Biological Transport / drug effects
  • Calcineurin / physiology
  • Calcium Signaling / drug effects
  • Calcium Signaling / genetics
  • Consensus Sequence
  • Cyclosporine / adverse effects
  • Cyclosporine / pharmacology
  • Cytokines / biosynthesis
  • Cytokines / genetics
  • DNA / metabolism
  • DNA-Binding Proteins / antagonists & inhibitors*
  • DNA-Binding Proteins / physiology
  • Drug Design
  • Gene Expression Regulation / drug effects*
  • Humans
  • Immune System / drug effects*
  • Immune System / metabolism
  • Immunosuppressive Agents / adverse effects
  • Immunosuppressive Agents / pharmacology*
  • Models, Immunological
  • NFATC Transcription Factors
  • Nuclear Proteins*
  • Phosphorylation / drug effects
  • Protein Binding / drug effects
  • Protein Processing, Post-Translational / drug effects
  • Tacrolimus / adverse effects
  • Tacrolimus / pharmacology
  • Transcription Factors / antagonists & inhibitors*
  • Transcription Factors / physiology
  • Transcription, Genetic / drug effects*

Substances

  • Cytokines
  • DNA-Binding Proteins
  • Immunosuppressive Agents
  • NFATC Transcription Factors
  • Nuclear Proteins
  • Transcription Factors
  • Cyclosporine
  • DNA
  • Calcineurin
  • Tacrolimus