Skip to main page content
Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
, 13 (5), 572-7

Multiresistance Genes of Rhizobium Etli CFN42


Multiresistance Genes of Rhizobium Etli CFN42

R González-Pasayo et al. Mol Plant Microbe Interact.

Erratum in

  • Mol Plant Microbe Interact 2000 Jul;13(7):796


Multidrug efflux pumps of bacteria are involved in the resistance to various antibiotics and toxic compounds. In Rhizobium etli, a mutualistic symbiont of Phaseolus vulgaris (bean), genes resembling multidrug efflux pump genes were identified and designated rmrA and rmrB. rmrA was obtained after the screening of transposon-generated fusions that are inducible by bean-root released flavonoids. The predicted gene products of rmrAB shared significant homology to membrane fusion and major facilitator proteins, respectively. Mutants of rmrA formed on average 40% less nodules in bean, while mutants of rmrA and rmrB had enhanced sensitivity to phytoalexins, flavonoids, and salicylic acid, compared with the wild-type strain. Multidrug resistance genes emrAB from Escherichia coli complemented an rmrA mutant from R. etli for resistance to high concentrations of naringenin.

Similar articles

See all similar articles

Cited by 34 PubMed Central articles

See all "Cited by" articles

Publication types

Associated data

LinkOut - more resources