Insights into the structural and functional evolution of plant genomes afforded by the nucleotide sequences of chromosomes 2 and 4 of Arabidopsis thaliana

Yeast. 2000 Apr;17(1):1-5. doi: 10.1002/(SICI)1097-0061(200004)17:1<1::AID-YEA3>3.0.CO;2-V.


The rapidly accumulating genome sequence data from the plant Arabidopsis thaliana allows more detailed analysis of genome content and organisation than ever before possible in plants. The genome shows a surprisingly high level of genetic redundancy, with as many as 75% of gene products showing significant homology to another protein of A. thaliana. Many duplicated genes occur in arrays of conserved order and indicate that A. thaliana is likely to have had a tetraploid ancestor. Analysis of the divergence of duplicated genome segments leads to the prediction of two major modes of plant genome evolution: macro-scale duplication and rearrangement of chromosomes and micro-scale translocations, duplication and loss of individual genes or small groups of genes.

Publication types

  • Review

MeSH terms

  • Arabidopsis / genetics*
  • Evolution, Molecular
  • Gene Duplication
  • Genome, Plant*
  • Polyploidy
  • Sequence Analysis, DNA
  • Translocation, Genetic