Abstract
Kamillosan(R) cream contains chamomile extract as active principle manufactured from the chamomile sort Manzana which is rich in active principles and has been proved not to exhibit a chamomile-related allergen potential. For this reason Kamillosan(R) cream is suited for local therapy of atopic eczema. In a partially double-blind, randomized study carried out as a half-side comparison, Kamillosan(R) cream was tested vs. 0.5% hydrocortisone cream and the vehicle cream as placebo in patients suffering from medium-degree atopic eczema. After a 2-week treatment Kamillosan(R) cream showed a mild superiority towards 0.5% hydrocortisone and a marginal difference as compared to placebo.
Publication types
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Clinical Trial
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Clinical Trial, Phase III
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Randomized Controlled Trial
MeSH terms
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Administration, Topical
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Anti-Inflammatory Agents / administration & dosage
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Arachidonic Acid / metabolism
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Arm
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Chamomile / therapeutic use
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Dermatitis, Atopic / drug therapy*
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Drug Combinations
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Erythema / drug therapy
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Humans
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Hydrocortisone / administration & dosage
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Middle Aged
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Oils, Volatile / administration & dosage*
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Phytotherapy
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Plant Extracts / administration & dosage*
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Plants, Medicinal
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Pruritus / drug therapy
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Sesquiterpenes / administration & dosage*
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Treatment Outcome
Substances
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Anti-Inflammatory Agents
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Drug Combinations
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Oils, Volatile
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Plant Extracts
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Sesquiterpenes
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Kamillosan
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Arachidonic Acid
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Hydrocortisone