DNA methylation inhibitors in the treatment of leukemias, myelodysplastic syndromes and hemoglobinopathies: clinical results and possible mechanisms of action

Curr Top Microbiol Immunol. 2000;249:135-64. doi: 10.1007/978-3-642-59696-4_9.
No abstract available

Publication types

  • Research Support, Non-U.S. Gov't
  • Review

MeSH terms

  • Antimetabolites, Antineoplastic / therapeutic use
  • Azacitidine / analogs & derivatives
  • Azacitidine / therapeutic use*
  • Clinical Trials as Topic
  • DNA Methylation / drug effects*
  • DNA Modification Methylases / antagonists & inhibitors*
  • Decitabine
  • Hemoglobinopathies / drug therapy*
  • Humans
  • Leukemia / drug therapy*
  • Myelodysplastic Syndromes / drug therapy*

Substances

  • Antimetabolites, Antineoplastic
  • Decitabine
  • DNA Modification Methylases
  • Azacitidine