Antisense oligonucleotides as a tool for gene functionalization and target validation

Biochim Biophys Acta. 1999 Dec 10;1489(1):19-30. doi: 10.1016/s0167-4781(99)00144-x.
No abstract available

Publication types

  • Review

MeSH terms

  • Animals
  • Enzyme-Linked Immunosorbent Assay
  • Gene Expression Regulation / drug effects
  • Gene Targeting / methods*
  • Genes / physiology*
  • Genetic Testing / methods
  • Human Genome Project
  • Humans
  • Oligonucleotides, Antisense / chemistry*
  • Oligonucleotides, Antisense / metabolism*
  • Oligonucleotides, Antisense / pharmacology
  • Protein Kinase C / antagonists & inhibitors
  • Protein Kinase C / genetics
  • RNA / genetics
  • RNA / metabolism
  • Reverse Transcriptase Polymerase Chain Reaction
  • Sequence Analysis, DNA / methods
  • Signal Transduction / drug effects
  • Signal Transduction / genetics
  • Substrate Specificity / genetics

Substances

  • Oligonucleotides, Antisense
  • RNA
  • Protein Kinase C