Yellow nail syndrome: resolution of yellow nails after successful treatment of breast cancer

Chest. 2000 May;117(5):1516-8. doi: 10.1378/chest.117.5.1516.


Yellow nail syndrome (YNS) is a rare entity of unknown cause in which congenitally hypoplastic lymphatics play a major role in the clinical manifestations of the disease. YNS has been associated with many malignancies and immune disorders. We report a case of new-onset YNS associated with breast cancer and dramatic improvement in the yellow nails with cancer treatment.

Publication types

  • Case Reports

MeSH terms

  • Breast Neoplasms / diagnosis*
  • Breast Neoplasms / therapy
  • Carcinoma, Ductal, Breast / diagnosis*
  • Carcinoma, Ductal, Breast / therapy
  • Combined Modality Therapy
  • Female
  • Follow-Up Studies
  • Humans
  • Middle Aged
  • Nail Diseases / diagnosis*
  • Nail Diseases / therapy
  • Paraneoplastic Syndromes / diagnosis*
  • Paraneoplastic Syndromes / therapy
  • Pigmentation Disorders / diagnosis*
  • Pigmentation Disorders / therapy