Cortical blindness in severe preeclampsia: computed tomography, magnetic resonance imaging, and single-photon-emission computed tomography findings

Obstet Gynecol. 2000 Jun;95(6 Pt 2):1017-9. doi: 10.1016/s0029-7844(00)00878-4.

Abstract

Background: Cortical blindness is a complication of severe preeclampsia, but it is unclear whether it results from cerebral vasospasm and ischemic injury or vasogenic (hydrostatic) edema due to increased capillary permeability.

Case: Reversible cortical blindness in a 33-year-old gravida 2, para 1, with severe postpartum preeclampsia after evacuation of a partial molar pregnancy at 19 weeks' gestation is presented. Initial neuroimaging studies showed hyperperfusion on head single-photon-emission computed tomography scan, which corresponded with lesions found on head computed tomography and magnetic resonance imaging scans. Follow-up neuroimaging studies 2 weeks later, by which time the patient's visual acuity had returned to normal, showed complete resolution of radiologic abnormalities.

Conclusion: Neuroimaging studies in a woman with severe postpartum preeclampsia complicated by reversible cortical blindness showed that blindness resulted from vasogenic (hydrostatic) cerebral edema and not cerebral vasospasm.

Publication types

  • Case Reports
  • Research Support, Non-U.S. Gov't
  • Research Support, U.S. Gov't, P.H.S.

MeSH terms

  • Adult
  • Blindness, Cortical / diagnosis
  • Blindness, Cortical / etiology*
  • Female
  • Humans
  • Magnetic Resonance Imaging
  • Occipital Lobe / diagnostic imaging
  • Occipital Lobe / pathology
  • Pre-Eclampsia / complications*
  • Pregnancy
  • Radiography
  • Temporal Lobe / diagnostic imaging
  • Temporal Lobe / pathology
  • Tomography, Emission-Computed, Single-Photon