Perforin: more than just an effector molecule

Immunol Today. 2000 Jun;21(6):254-6. doi: 10.1016/s0167-5699(00)01622-4.
No abstract available

Publication types

  • Review

MeSH terms

  • Animals
  • Autoimmune Diseases / genetics
  • Autoimmune Diseases / immunology
  • Autoimmunity
  • Child, Preschool
  • Chromosomes, Human, Pair 10 / genetics
  • Cytoplasmic Granules / metabolism
  • Cytotoxicity, Immunologic*
  • Fas Ligand Protein
  • Feedback
  • Histiocytosis, Non-Langerhans-Cell / genetics
  • Humans
  • Infant
  • Killer Cells, Natural / immunology
  • Lymphocyte Activation
  • Lymphocytic Choriomeningitis / immunology
  • Lymphocytic choriomeningitis virus / physiology
  • Lymphoproliferative Disorders / genetics
  • Lymphoproliferative Disorders / immunology
  • Membrane Glycoproteins / deficiency
  • Membrane Glycoproteins / genetics
  • Membrane Glycoproteins / immunology
  • Membrane Glycoproteins / physiology*
  • Mice
  • Mice, Inbred C57BL
  • Mice, Inbred MRL lpr
  • Mice, Knockout
  • Perforin
  • Pore Forming Cytotoxic Proteins
  • T-Lymphocytes, Cytotoxic / immunology
  • Virus Latency

Substances

  • FASLG protein, human
  • Fas Ligand Protein
  • Fasl protein, mouse
  • Membrane Glycoproteins
  • Pore Forming Cytotoxic Proteins
  • Perforin