Perspective: The insulin signaling system--a common link in the pathogenesis of type 2 diabetes

Endocrinology. 2000 Jun;141(6):1917-21. doi: 10.1210/endo.141.6.7584.
No abstract available

Publication types

  • Review

MeSH terms

  • Animals
  • Diabetes Mellitus, Type 2 / etiology*
  • Diabetes Mellitus, Type 2 / physiopathology
  • Humans
  • Insulin / physiology*
  • Insulin Receptor Substrate Proteins
  • Insulin-Like Growth Factor I / physiology
  • Intracellular Signaling Peptides and Proteins
  • Islets of Langerhans / physiopathology
  • Phosphoproteins / physiology
  • Receptor, Insulin / physiology
  • Signal Transduction*

Substances

  • IRS1 protein, human
  • IRS2 protein, human
  • Insulin
  • Insulin Receptor Substrate Proteins
  • Intracellular Signaling Peptides and Proteins
  • Phosphoproteins
  • Insulin-Like Growth Factor I
  • Receptor, Insulin