Design and synthesis of new biomimetic materials

J Inorg Biochem. 2000 Apr;79(1-4):93-6. doi: 10.1016/s0162-0134(99)00176-2.

Abstract

In this paper, it is reported that the histidine-silane derivative Boc-His(Boc)-CONH-(CH2)3Si(OEt)3 can be polymerized via the sol-gel method or can be grafted on a silica surface. The obtained organosilicas bear histidine molecules covalently bonded on the inorganic matrix. Their Cu(II) complexes have been evaluated as oxidation catalysts for the conversion of 3,5-di-tert-butylcatechol (DTBC) to 3,5-di-tert-butylquinone (DTBQ) in the presence of dioxygen.

MeSH terms

  • Catalysis
  • Catechols / chemistry*
  • Drug Design
  • Histidine / analogs & derivatives*
  • Histidine / chemical synthesis
  • Histidine / chemistry
  • Indicators and Reagents
  • Magnetic Resonance Spectroscopy
  • Models, Molecular
  • Molecular Conformation
  • Organosilicon Compounds / chemical synthesis
  • Organosilicon Compounds / chemistry*
  • Oxidation-Reduction
  • Oxygen*
  • Silanes

Substances

  • Catechols
  • Indicators and Reagents
  • Organosilicon Compounds
  • Silanes
  • tert-butyloxycarbonyl-histidine(tert-butyloxycarbonyl) 3-(triethoxysilyl)propyl amide
  • 3,5-di-tert-butylcatechol
  • Histidine
  • Oxygen