Current concepts of respiratory complications of neuromuscular disease in children

Curr Opin Pediatr. 2000 Jun;12(3):203-7. doi: 10.1097/00008480-200006000-00004.


Chronic neuromuscular diseases affect the respiratory muscles in varying patterns and degrees. As a result, patients with these disorders develop restrictive pulmonary disease, ineffective cough, atelectasis and pneumonia, and chronic respiratory insufficiency leading to respiratory failure. Therapeutic strategies are evolving to augment cough and airway clearance, improve lung volumes, and support the patient with progressive ventilatory failure. These techniques have improved longevity and quality of life for many patients with neuromuscular disease.

Publication types

  • Review

MeSH terms

  • Child
  • Humans
  • Lung Diseases / diagnosis
  • Lung Diseases / etiology*
  • Lung Diseases / therapy
  • Neuromuscular Diseases / complications*
  • Neuromuscular Diseases / diagnosis
  • Neuromuscular Diseases / therapy
  • Prognosis
  • Respiratory Insufficiency / diagnosis
  • Respiratory Insufficiency / etiology*
  • Respiratory Insufficiency / therapy