Electron arc therapy treatment planning verification with alanine/EPR dosimetry

Appl Radiat Isot. 2000 May;52(5):1203-7. doi: 10.1016/s0969-8043(00)00072-5.

Abstract

Alanine/EPR dosimetry was applied to measure dose distributions during electron arc therapy treatments generated by electron beams moving isocentrically over a stated arc. Alanine-polyethylene pellets, prepared at ISS according to the NIST recipe, inserted in a homogeneous cylindrical and anthropomorphic phantoms, were used. Preliminary, alanine response to static electron beams in the (6-20) MeV nominal energy range was studied. Then alanine dosimetry was applied to determine the dose versus the gantry angle at a reference point in a cylindrical homogeneous phantom. Finally, arc therapy treatment planning verification was performed in anthropomorphic phantom.

MeSH terms

  • Alanine / radiation effects
  • Electron Spin Resonance Spectroscopy / methods*
  • Electrons / therapeutic use*
  • Humans
  • Phantoms, Imaging
  • Polyethylene
  • Radiotherapy Planning, Computer-Assisted / methods*
  • Radiotherapy, High-Energy

Substances

  • Polyethylene
  • Alanine