Delivering copper within plant cells

Curr Opin Plant Biol. 2000 Jun;3(3):205-10.


Two genes recently identified in Arabidopsis thaliana may be involved in sequestering free copper ions in the cytoplasm and delivering copper to post-Golgi vesicles. The genes COPPER CHAPERONE and RESPONSIVE TO ANTAGONIST1 are homologous to copper-trafficking genes from yeast and humans. This plant copper-delivery pathway is required to create functional ethylene receptors. The pathway may also facilitate the transport of copper from senescing leaf tissue. In addition, several other genes have been identified recently that may have a role in copper salvage during senescence.

Publication types

  • Research Support, Non-U.S. Gov't
  • Research Support, U.S. Gov't, Non-P.H.S.
  • Review

MeSH terms

  • Arabidopsis Proteins*
  • Biological Transport
  • Cation Transport Proteins*
  • Copper / metabolism*
  • Copper Transport Proteins
  • Ethylenes / metabolism
  • Plant Cells
  • Plant Development
  • Plants / metabolism*
  • Protein Kinases / physiology


  • Arabidopsis Proteins
  • Cation Transport Proteins
  • Copper Transport Proteins
  • Ethylenes
  • RAN1 protein, Arabidopsis
  • Copper
  • ethylene
  • Protein Kinases