Multiple site silicon-based probes for chronic recordings in freely moving rats: implantation, recording and histological verification

J Neurosci Methods. 2000 May 15;98(1):77-82. doi: 10.1016/s0165-0270(00)00193-x.


This paper describes the procedure of assembling a miniature microdrive and silicon probe system for surgical implantation into the adult rat brain. Successful recordings of single and multiunit activity with parallel depth profiles of spontaneous and evoked field potentials are shown. The procedure for histological verification of the position of the silicon probe is described.

Publication types

  • Research Support, U.S. Gov't, P.H.S.

MeSH terms

  • Age Factors
  • Animals
  • Brain / physiology*
  • Electrodes, Implanted*
  • Electrophysiology / instrumentation*
  • Electrophysiology / methods*
  • Evoked Potentials / physiology
  • Locomotion / physiology*
  • Rats
  • Silicon*


  • Silicon