SOX8 expression during chick embryogenesis

Mech Dev. 2000 Jun;94(1-2):257-60. doi: 10.1016/s0925-4773(00)00296-3.


We have isolated the SOX8 gene from the chicken embryo. This gene shows a high degree of sequence homology to SOX9 and SOX10. Detailed analysis of SOX8 expression by whole-mount in situ shows a dynamic and restricted expression pattern during chick development. SOX8 is expressed in the somitic derivative, the dermomyotome, the developing heart, pancreas, enteric neurone system, limb and the neural tube. This is the first detailed expression analysis of SOX8 in any species

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Amino Acid Sequence
  • Animals
  • Chick Embryo
  • DNA-Binding Proteins / genetics*
  • DNA-Binding Proteins / metabolism
  • Extremities / embryology
  • Gene Expression Regulation, Developmental*
  • Molecular Sequence Data
  • Muscle, Skeletal / embryology
  • Pancreas / embryology
  • Sequence Homology, Amino Acid
  • Transcription Factors / genetics*
  • Transcription Factors / metabolism


  • DNA-Binding Proteins
  • Transcription Factors

Associated data

  • GENBANK/AF228664