Mannheim classification of nongenomically initiated (rapid) steroid action(s)

J Clin Endocrinol Metab. 2000 May;85(5):2072-5. doi: 10.1210/jcem.85.5.6516.


There is increasing evidence for rapid effects of steroids that are incompatible with the classical model of genomic steroid action. To address the diversity of mechanisms for rapid steroid signaling described over the past years, a classification of rapid steroid effects has been proposed to promote the discussion and understanding of nongenomic steroid action.

Publication types

  • Review

MeSH terms

  • Animals
  • Genome*
  • Humans
  • Receptors, Steroid / physiology*
  • Steroids / physiology*
  • Transcription, Genetic*


  • Receptors, Steroid
  • Steroids