Natural and synthetic inhibitors of the tumor-associated serine protease urokinase-type plasminogen activator

Adv Exp Med Biol. 2000;477:331-41. doi: 10.1007/0-306-46826-3_36.
No abstract available

Publication types

  • Research Support, Non-U.S. Gov't
  • Review

MeSH terms

  • Amidines / chemical synthesis
  • Amidines / pharmacology
  • Amiloride / chemistry
  • Amiloride / pharmacology
  • Animals
  • Benzamidines / chemistry
  • Benzamidines / pharmacology
  • Guanidines / chemistry
  • Guanidines / pharmacology
  • Mice
  • Mice, Knockout
  • Models, Biological
  • Molecular Structure
  • Neoplasm Invasiveness
  • Neoplasm Proteins / antagonists & inhibitors*
  • Neoplasm Proteins / metabolism
  • Phenotype
  • Plasminogen Activator Inhibitor 1 / deficiency
  • Plasminogen Activator Inhibitor 1 / genetics
  • Plasminogen Activator Inhibitor 1 / pharmacology
  • Plasminogen Activator Inhibitor 1 / physiology
  • Plasminogen Activator Inhibitor 2 / deficiency
  • Plasminogen Activator Inhibitor 2 / genetics
  • Plasminogen Activator Inhibitor 2 / pharmacology
  • Plasminogen Activator Inhibitor 2 / physiology
  • Receptors, Cell Surface / drug effects
  • Receptors, Cell Surface / metabolism
  • Receptors, Urokinase Plasminogen Activator
  • Serine Proteinase Inhibitors / chemical synthesis
  • Serine Proteinase Inhibitors / pharmacology*
  • Serpins / physiology*
  • Structure-Activity Relationship
  • Thiophenes / chemical synthesis
  • Thiophenes / pharmacology
  • Urokinase-Type Plasminogen Activator / antagonists & inhibitors*

Substances

  • 4-iodine-benzo(b)thiophene-2-carboxamidine
  • Amidines
  • B 623
  • Benzamidines
  • Guanidines
  • Neoplasm Proteins
  • Plasminogen Activator Inhibitor 1
  • Plasminogen Activator Inhibitor 2
  • Plaur protein, mouse
  • Receptors, Cell Surface
  • Receptors, Urokinase Plasminogen Activator
  • Serine Proteinase Inhibitors
  • Serpins
  • Thiophenes
  • phenylguanidine
  • 4-aminobenzamidine
  • Amiloride
  • Urokinase-Type Plasminogen Activator