Aromatic Hydrocarbon Dioxygenases in Environmental Biotechnology

Curr Opin Biotechnol. 2000 Jun;11(3):236-43. doi: 10.1016/s0958-1669(00)00090-2.


Aromatic hydrocarbon dioxygenases belong to a large family of Rieske non-heme iron oxygenases. The dioxygenases have a broad substrate specificity and catalyze enantiospecific reactions with a wide range of substrates. These characteristics make them attractive synthons for the production of industrially and medically important chiral chemicals and also provide essential information for the development of bioremediation technology.

Publication types

  • Research Support, Non-U.S. Gov't
  • Research Support, U.S. Gov't, P.H.S.
  • Review

MeSH terms

  • Biodegradation, Environmental
  • Biotechnology*
  • Hydrocarbons, Aromatic
  • Oxygenases / chemistry
  • Oxygenases / classification
  • Oxygenases / metabolism*
  • Phylogeny
  • Structure-Activity Relationship
  • Substrate Specificity
  • Terminology as Topic


  • Hydrocarbons, Aromatic
  • Oxygenases