Biocontrol ability of fluorescent pseudomonads genetically dissected: importance of positive feedback regulation

Curr Opin Biotechnol. 2000 Jun;11(3):290-7. doi: 10.1016/s0958-1669(00)00098-7.


Root diseases caused by fungal pathogens can be suppressed by certain rhizobacteria that effectively colonize the roots and produce extracellular antifungal compounds. To be effective, biocontrol bacteria need to be present at sufficiently high cell densities. These conditions favor the operation of positive feedback mechanisms that control the production of antifungal compounds in biocontrol strains of fluorescent pseudomonads, via both transcriptional and post-transcriptional mechanisms.

Publication types

  • Research Support, Non-U.S. Gov't
  • Review

MeSH terms

  • Anti-Bacterial Agents / biosynthesis
  • Antifungal Agents / metabolism
  • Biotechnology
  • Feedback
  • Fungi / pathogenicity
  • Genes, Bacterial
  • Genetic Engineering
  • Multigene Family
  • Plant Diseases / microbiology*
  • Plant Roots / microbiology
  • Pseudomonas fluorescens / genetics*
  • Pseudomonas fluorescens / physiology*
  • Soil Microbiology


  • Anti-Bacterial Agents
  • Antifungal Agents