Synaptic kainate receptors

Curr Opin Neurobiol. 2000 Jun;10(3):342-51. doi: 10.1016/s0959-4388(00)00094-5.


Kainate receptors are a family of ionotropic glutamate receptors with poorly understood functions. Recent evidence firmly establishes kainate receptors as postsynaptic mediators of synaptic transmission. A second, presynaptic, modulatory role of kainate receptors has also been suggested, although the mechanism(s) involved remain controversial.

Publication types

  • Research Support, Non-U.S. Gov't
  • Research Support, U.S. Gov't, P.H.S.
  • Review

MeSH terms

  • Animals
  • Excitatory Postsynaptic Potentials / physiology
  • Neurons / chemistry
  • Neurons / physiology*
  • Receptors, Kainic Acid / analysis
  • Receptors, Kainic Acid / physiology*
  • Synapses / chemistry
  • Synapses / physiology*


  • Receptors, Kainic Acid