Rhenium-188--a generator-derived radioisotope for cancer therapy

Cancer Biother Radiopharm. 1998 Oct;13(5):337-49. doi: 10.1089/cbr.1998.13.337.

Abstract

Rhenium-188 (188Re) is an important therapeutic radioisotope which is obtained on demand as carrier-free sodium perrhenate by saline elution of the tungsten-188/rhenium-188 generator system. With a half-life of 16.9 hours and emission of a high energy beta particle (maximal energy of 2.12 MeV) and a gamma photon (155 keV, 15%) for imaging, 188Re can be provided at reasonable costs for routine preparation of radiopharmaceuticals for cancer treatment.

Publication types

  • Research Support, U.S. Gov't, Non-P.H.S.
  • Review

MeSH terms

  • Half-Life
  • Humans
  • Neoplasms / radiotherapy*
  • Radioisotopes / therapeutic use*
  • Radiopharmaceuticals / chemical synthesis
  • Radiopharmaceuticals / therapeutic use*
  • Rhenium / therapeutic use*

Substances

  • Radioisotopes
  • Radiopharmaceuticals
  • Rhenium