Changes in hepatic cytochrome P450 enzymes by biodegradation products of 4-tert-octylphenol polyethoxylate in rats

Bull Environ Contam Toxicol. 2000 Jun;64(6):804-10. doi: 10.1007/s0012800074.

Authors

N Hanioka¹, T Tanaka-Kagawa, Y S Chung, T Nishimura, H Jinno, M Ando

Affiliation

¹ Division of Environmental Chemistry, National Institute of Health Sciences, 1-18-1 Kamiyoga, Setagaya-ku, Tokyo 158-8501, Japan.

PMID: 10856336
DOI: 10.1007/s0012800074

No abstract available

Publication types

Research Support, Non-U.S. Gov't

MeSH terms

Animals
Biodegradation, Environmental
Body Weight / drug effects
Cytochrome P-450 Enzyme Inhibitors
Cytochrome P-450 Enzyme System / metabolism*
Immunoblotting
Isoenzymes / metabolism
Liver / drug effects*
Liver / enzymology
Male
Microsomes, Liver / drug effects
Microsomes, Liver / enzymology
Organ Size / drug effects
Phenols / toxicity*
Rats
Rats, Sprague-Dawley
Surface-Active Agents / toxicity*
Water Pollutants, Chemical / toxicity

Substances

Cytochrome P-450 Enzyme Inhibitors
Isoenzymes
Phenols
Surface-Active Agents
Water Pollutants, Chemical
Cytochrome P-450 Enzyme System
4-tert-octylphenol