Intracellular cholesterol trafficking: role of the NPC1 protein

Biochim Biophys Acta. 2000 Jun 26;1486(1):171-83. doi: 10.1016/s1388-1981(00)00055-x.
No abstract available

Publication types

  • Review

MeSH terms

  • Androstenes / pharmacology
  • Animals
  • Biological Transport
  • CHO Cells
  • Carrier Proteins*
  • Cell Membrane / metabolism*
  • Cholesterol / biosynthesis
  • Cholesterol / metabolism*
  • Cholesterol, LDL / metabolism
  • Cricetinae
  • Endocytosis
  • Endoplasmic Reticulum / metabolism
  • Fibroblasts
  • Golgi Apparatus / drug effects
  • Golgi Apparatus / metabolism
  • Homeostasis
  • Humans
  • Intracellular Signaling Peptides and Proteins
  • Membrane Glycoproteins*
  • Mutation
  • Niemann-Pick C1 Protein
  • Proteins / chemistry
  • Proteins / genetics
  • Proteins / metabolism*
  • Signal Transduction
  • Transfection

Substances

  • Androstenes
  • Carrier Proteins
  • Cholesterol, LDL
  • Intracellular Signaling Peptides and Proteins
  • Membrane Glycoproteins
  • NPC1 protein, human
  • Niemann-Pick C1 Protein
  • Proteins
  • 3-beta-(2-(diethylamino)ethoxy)androst-5-en-17-one
  • Cholesterol