Towards optimal recording and analysis of the mismatch negativity

Audiol Neurootol. May-Aug 2000;5(3-4):235-46. doi: 10.1159/000013885.


In this paper, the conceptual and practical issues related to the measurement of mismatch negativity (MMN) are discussed from the viewpoint of cost-efficiency. First, various criteria for efficiency or optimality of measurements are described, including reliability and signal-to-noise ratio. Then a critical look is taken at some currently used concepts and data analysis methods. Practical guidelines for the measurement and analysis of MMN are given, complementing the earlier reviews on the subject. Finally, reliability studies on MMN are critically reviewed.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Auditory Pathways / physiopathology
  • Brain Mapping
  • Contingent Negative Variation / physiology*
  • Cost-Benefit Analysis
  • Electroencephalography / economics*
  • Evoked Potentials, Auditory / physiology*
  • Humans
  • Magnetoencephalography / economics*
  • Predictive Value of Tests
  • Reaction Time / physiology
  • Signal Processing, Computer-Assisted*