An experimental study was made on wheat-germ oil as a source of easily assimilable vitamin E. In rats, the above oil intake results in a rapid increase in the content of vitamin E in the brain, liver, heart, lungs, kidneys, and spleen. There has been studied a change in the intensity of lipid peroxidation processes. It is shown that in oral administration wheat germ oil efficiently saturates the body with vitamin E. In all tissues, the work of the [symbol: see text]-tocopherol redox-system is noted to be stimulated, LPO inhibited, with eicosanoid synthesis proceeding under immediate control of the system of fat-soluble vitamins. The total state of dynamic equilibrium in the LPO-AOA system has effectively shifted to the side of predominance of the AD system components. The total tissue AOA remained stable in most organs.