Alzheimer's disease. Closing in on gamma-secretase

Nature. 2000 Jun 8;405(6787):627, 629. doi: 10.1038/35015193.
No abstract available

Publication types

  • News

MeSH terms

  • Alzheimer Disease / enzymology*
  • Amyloid Precursor Protein Secretases
  • Amyloid beta-Peptides / metabolism
  • Amyloid beta-Protein Precursor / metabolism
  • Animals
  • Aspartic Acid Endopeptidases
  • Endopeptidases / adverse effects
  • Endopeptidases / metabolism*
  • Enzyme Inhibitors / pharmacology
  • Membrane Proteins / adverse effects
  • Membrane Proteins / metabolism*
  • Mice
  • Presenilin-1
  • Presenilin-2

Substances

  • Amyloid beta-Peptides
  • Amyloid beta-Protein Precursor
  • Enzyme Inhibitors
  • Membrane Proteins
  • Presenilin-1
  • Presenilin-2
  • Amyloid Precursor Protein Secretases
  • Endopeptidases
  • Aspartic Acid Endopeptidases
  • Bace1 protein, mouse