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. 2000 Jun 24;320(7251):1720-3.

doi: 10.1136/bmj.320.7251.1720.

Seeing what you want to see in randomised controlled trials: versions and perversions of UKPDS data. United Kingdom prospective diabetes study

J McCormack¹, T Greenhalgh

Affiliations

PMID: 10864554
PMCID: PMC1127485
DOI: 10.1136/bmj.320.7251.1720

Seeing what you want to see in randomised controlled trials: versions and perversions of UKPDS data. United Kingdom prospective diabetes study

J McCormack et al. BMJ. 2000.

. 2000 Jun 24;320(7251):1720-3.

doi: 10.1136/bmj.320.7251.1720.

Authors

J McCormack¹, T Greenhalgh

Affiliation

¹ Faculty of Pharmaceutical Sciences, University of British Columbia, Vancouver, Canada V6T 1W5. jmccorma@interchange.ubc.ca

PMID: 10864554
PMCID: PMC1127485
DOI: 10.1136/bmj.320.7251.1720

No abstract available

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Comment in

Seeing what you want to see in randomised controlled trials. Authors' choice of study was ill informed.
Holman R. Holman R. BMJ. 2000 Oct 28;321(7268):1078-9. doi: 10.1136/bmj.321.7268.1078. BMJ. 2000. PMID: 11053192 Free PMC article. No abstract available.
Seeing what you want to see in randomised controlled trials. Meta- analyses may suffer from interpretation bias too.
Lindbaek M. Lindbaek M. BMJ. 2000 Oct 28;321(7268):1079. BMJ. 2000. PMID: 11053193 No abstract available.
Glycaemia and vascular effects of type 2 diabetes. Lowering glucose concentrations may not be of any value in itself.
Budenholzer B. Budenholzer B. BMJ. 2001 May 19;322(7296):1245-6; author reply 1247. BMJ. 2001. PMID: 11388182 Free PMC article. No abstract available.
Interpretation of randomised trials is indeed open to debate.
Conradi P, Taylor D. Conradi P, et al. BMJ. 2003 Sep 27;327(7417):752. doi: 10.1136/bmj.327.7417.752-b. BMJ. 2003. PMID: 14512497 Free PMC article. No abstract available.

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References

1. University Group Diabetes Program. A study of the effects of hypoglycemic agents on vascular complications in patients with adult-onset diabetes. Diabetes. 1970;19(suppl 2):747–830. - PubMed
1. UK Prospective Diabetes Study (UKPDS) Group. Intensive blood-glucose control with sulphonylureas or insulin compared with conventional treatment and risk of complications in patients with type 2 diabetes (UKPDS 33) Lancet. 1998;352:837–853. - PubMed
1. UK Prospective Diabetes Study (UKPDS) Group. Effect of intensive blood-glucose control with metformin on complications in overweight patients with type 2 diabetes (UKPDS 34) Lancet. 1998;352:854–865. - PubMed
1. Ewart R. The UKPDS—what was the question? Lancet. 1999;353:1882. - PubMed
1. Bailey CJ, Grant PJ. The UK prospective diabetes study [letter] Lancet. 1998;352:1932. - PubMed

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