Evolution-driving genes

Res Microbiol. 2000 Mar;151(2):91-5. doi: 10.1016/s0923-2508(00)00122-4.


Genomic sequences provide evidence for a common origin of life and its evolution via selection of genetic variants created by mutation and recombination. Two classes of genes are known to accelerate mutation and/or recombination rates in bacterial populations: stress-inducible wild-type genes, usually part of the SOS regulon, and genes whose functional loss, or downregulation, increases the rate of genetic variability (mutator and/or hyper-rec mutants).

Publication types

  • Research Support, Non-U.S. Gov't
  • Review

MeSH terms

  • Bacteria / genetics*
  • Bacteria / growth & development
  • Evolution, Molecular*
  • Mutation*
  • Recombination, Genetic*
  • Selection, Genetic