Detecting hypermutations in viral sequences with an emphasis on G --> A hypermutation

Bioinformatics. 2000 Apr;16(4):400-1. doi: 10.1093/bioinformatics/16.4.400.


Summary: This program compares sequence sets to a reference sequence, tallies G --> A hypermutations, and presents the results in various tables and graphs, which include dinucleotide context, summaries of all observed nucleotide changes, and stop codons introduced by hypermutation.


Publication types

  • Research Support, U.S. Gov't, Non-P.H.S.
  • Research Support, U.S. Gov't, P.H.S.

MeSH terms

  • Adenine*
  • Animals
  • Guanine*
  • Humans
  • Point Mutation*
  • Software*
  • Viruses / genetics*


  • Guanine
  • Adenine