Sorting and transport in C. elegans: aA model system with a sequenced genome

Curr Opin Cell Biol. 2000 Aug;12(4):517-23. doi: 10.1016/s0955-0674(00)00125-3.


In the past few years, yeast and cultured cells have been the model systems of choice for the study of protein sorting and transport. Recently, there has been a surge in research in these areas in Caenorhabditis elegans, with advances in experimental techniques and genomics. New in vivo assays that monitor endocytosis and neuronal transport have been used to delineate roles for several genes in these processes.

Publication types

  • Research Support, Non-U.S. Gov't
  • Research Support, U.S. Gov't, P.H.S.
  • Review

MeSH terms

  • Animals
  • Biological Transport / genetics
  • Caenorhabditis elegans / genetics*
  • Caenorhabditis elegans / metabolism*
  • Cell Membrane / metabolism
  • Dendrites / metabolism
  • Dyneins / metabolism
  • Endocytosis / physiology
  • Genes, Helminth*
  • Kinesin / metabolism
  • Models, Genetic
  • Neurons, Afferent / metabolism
  • Receptors, Cell Surface / metabolism


  • Receptors, Cell Surface
  • Dyneins
  • Kinesin