Transport between ER and Golgi

Curr Opin Cell Biol. 2000 Aug;12(4):445-9. doi: 10.1016/s0955-0674(00)00115-0.

Abstract

In the last eighteen months, it has become clear that some classes of proteins are actively recruited into endoplasmic reticulum export carriers, whereas others are exported as bulk-flow cargo. Subsequent transport to the Golgi is mediated by tubulovesicular membranes. The anterograde membrane flow is compensated for by a retrograde pathway, which, in addition to the recycling of membrane and proteins to the endoplasmic reticulum, may play a role in anterograde cargo concentration.

Publication types

  • Review

MeSH terms

  • Animals
  • Biological Transport
  • Carrier Proteins / metabolism
  • Coat Protein Complex I / metabolism
  • Coated Vesicles / metabolism
  • Endoplasmic Reticulum / metabolism*
  • Golgi Apparatus / metabolism*
  • Phosphoproteins / metabolism
  • Saccharomyces cerevisiae Proteins*
  • Solubility
  • Vesicular Transport Proteins

Substances

  • Carrier Proteins
  • Coat Protein Complex I
  • Phosphoproteins
  • SEC31 protein, S cerevisiae
  • Saccharomyces cerevisiae Proteins
  • Vesicular Transport Proteins