Connecting vesicle transport to the cytoskeleton

Curr Opin Cell Biol. 2000 Aug;12(4):503-8. doi: 10.1016/s0955-0674(00)00123-x.


The cytoskeleton is crucial for the efficient and polarized transport of vesicles in intracellular membrane-sorting pathways. Recent studies have identified specific kinesin, dynein, and myosin motor proteins that mediate defined membrane transport steps. Important clues have also been uncovered about the nature of motor-protein receptors on vesicular cargoes and the molecular mechanisms of motor-protein regulation.

Publication types

  • Review

MeSH terms

  • Animals
  • Biological Transport
  • Carrier Proteins / metabolism*
  • Cytoskeleton / metabolism*
  • Microtubule-Associated Proteins / metabolism*


  • Carrier Proteins
  • Microtubule-Associated Proteins