Evolution of parasite virulence against qualitative or quantitative host resistance

Proc Biol Sci. 2000 May 22;267(1447):985-90. doi: 10.1098/rspb.2000.1100.

Abstract

We analysed the effects of two different modes of host resistance on the evolution of parasite virulence. Hosts can either adopt an all-or-nothing qualitative response (i.e. resistant hosts cannot be infected) or a quantitative form of resistance (i.e. which reduces the within-host growth rate of the parasite). We show that the mode of host resistance greatly affects the evolutionary outcome. Specifically, a qualitative form of resistance reduces parasite virulence, while a quantitative form of resistance generally selects for higher virulence.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Animals
  • Biological Evolution*
  • Host-Parasite Interactions
  • Models, Biological
  • Parasites / immunology
  • Parasites / pathogenicity*
  • Virulence